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Wolfson Brain Imaging Centre

Department of Clinical Neurosciences
 

Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using 31P magnetic resonance spectroscopy

Dr Alison Sleigh has designed a novel in-scanner exercise method which is patient-focused, inexpensive, remarkably simple and highly portable. As the cost, complexity and physical demands of specialised MR-compatible ergometers appears to be limiting the wider application of this technique in clinical research, this new method offers the opportunity to implement measurements of muscle mitochondrial function more widely and in new cohorts of growing clinical interest.

This article is published in Scientific Reports:

http://www.nature.com/articles/srep19057