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Wolfson Brain Imaging Centre

Department of Clinical Neurosciences

Studying at Cambridge

SR15786 Research Associate (Fixed Term)

Wolfson Brain Imaging Centre

Chris Rodgers' group at the Wolfson Brain Imaging Centre invite applications for a 3-year Postdoctoral Research Associate position to commence as soon as possible. This is an opportunity to develop novel methods for metabolic imaging with multinuclear MRI using a new multinuclear whole-body coil soon to be installed in the Siemens 7T Terra MRI scanner at the University of Cambridge.

This post is funded by an EU Future and Emerging Technologies grant to develop "Non-Invasive Chemistry Imaging in the Whole Human Body" (the NICI consortium). The post-holder will work closely with MR Coils BV (Netherlands), Prof Klomp's group (Utrecht), and Siemens to facilitate the integration of a new quintuple-tuned whole-body 7T transmit coil and receive array with 32kW multinuclear amplifier on the Siemens 7T Terra MRI scanner in Cambridge. This will enable imaging and spectroscopy of 1H, 19F, 31P, 23Na, and 13C containing metabolites across the body, with a particular focus on the human liver. The post-holder will implement a suite of software for post-processing and data analysis of multinuclear metabolic imaging data from scanners at Cambridge (Siemens 7T), Amsterdam (Philips 7T) and Pisa (GE 7T). The post-holder will work with these other 7T sites to standardise pulse sequences across platforms, and to validate them in phantoms and normal volunteers in a "travelling bodies" study. The post-holder will implement a data archive in Cambridge for the consortium. The post-holder will then work with colleagues in the Dept of Oncology (Cambridge) and at the other sites to conduct the first multi-nuclear, multi-vendor, multi-site 7T clinical study ¿ using 7T metabolic imaging to assess the response to chemotherapy of liver metastases in patients with colorectal cancer very shortly after treatment.

The post-holder will play a key role in Chris Rodgers' growing 7T MRI Physics Group in Cambridge. The post-holder will also work closely with Chris Rodgers' Cardiac Spectroscopy Group at the University Oxford who are using a whole-body 7T 31P-only coil to study cardiac metabolism in patients with cardiomyopathies in a separate project funded by the Wellcome Trust and the Royal Society. The post-holder will port the Oxford cardiac pulse sequences and data analysis tools to the 7T Terra platform and extend them for use in the liver. The role will also require close collaboration with clinical colleagues in the Dept of Oncology at Cambridge, and with members of the NICI consortium, particularly partners in Utrecht, Amsterdam, and Pisa, and at Siemens, Philips and GE.

Fixed-term: The funds for this post are available until 31 May 2021 in the first instance.

This appointment requires a Research Passport application.

To apply online for this vacancy, please go to http://www.jobs.cam.ac.uk/job/17750/ and click on the ‘Apply’ button. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV), a covering letter, a list of publications in PubMed citation format, and a statement of how your experience matches the role requirements above (max 2 pages) in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

If you have any questions about this vacancy or the application process, please contact Chris Rodgers (ctr28@cam.ac.uk, +44 1223336291). If you are attending the ISMRM 2018 meeting in Paris, Chris Rodgers would be delighted to meet with you to explain more about the role, and to see the work you are presenting.

Closing Date: 3rd July 2018

Interview Date: w/c 9th July 2018

Please quote reference SR15786 on your application and in any correspondence about this vacancy.

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