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Wolfson Brain Imaging Centre

Department of Clinical Neurosciences
 

Senior Research Associate

Wolfson Brain Imaging Centre

+44(0)1223 746460

as626@cam.ac.uk

ORCID: orcid.org/0000-0002-3859-8701

                                                                                              

Alison is an independent scientist who designs novel magnetic resonance spectroscopy for use in metabolic research. She has worked at the WBIC since 2003 and is affiliated to both the NIHR Cambridge Clinical Research Facility and Wellcome - MRC Institute of Metabolic Science. Her interests relate to the applications of magnetic resonance, in particular to mitochondrial function as well as in studying insulin resistance.  

 

Recent publications

Savage DB, Watson L, Carr K, Adams C, Brage S, Chatterjee KK, Hodson L, Boesch C, Kemp GJ, & Sleigh A. (2019). Accumulation of saturated intramyocellular lipid is associated with insulin resistance. The Journal of Lipid Research, 60, 1323-1332.

Charles-Edwards G, Amaral N, Sleigh A, Ayis S, Catibog N et al. (2019). Effect of iron isomaltoside on skeletal muscle energetics in patients with chronic heart failure and iron deficiency. Circulation, 139(21), 2386-2398.

Thankamony A, Kemp GJ, Koulman A, Bokii V, Savage DB, Boesch C, Hodson L, Dunger DB, & Sleigh A. (2018). Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis. Sci Rep, 8(1), 2750.

Stovell MG, Yan J-L, Sleigh A, Mada MO, Carpenter TA, Hutchinson PJA, & Carpenter KLH. (2017). Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications. Front Neurol, 8, 426.

Rocha N, Bulger DA, Frontini A, Titheradge H, Gribsholt SB et al. (2017). Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression. Elife, 6.

 

Internal collaborators at         

Wellcome-MRC Institute of Metabolic Science, Cambridge

NIHR Cambridge Clinical Research Facility, Cambridge

Cambridge Intellectual and Developmental Disabilities Research Group, Cambridge

and Prof Patrick Chinnery, MRC Mitochondrial Biology Unit, Cambridge

and Prof Kevin Brindle, CRUK Cambridge Institute, Cambridge

 

External collaborators

Prof Graham Kemp, University of Liverpool, Liverpool, UK

Prof Leanne Hodson, University of Oxford, Oxford, UK

Prof Chris Boesch, University Bern, Switzerland