Principal Research Associate
Wolfson Brain Imaging Centre
+44(0)1223 746460
ORCID: orcid.org/0000-0002-3859-8701
Alison is an independent scientist who designs novel magnetic resonance spectroscopy for use in metabolic research. She has worked at the WBIC since 2003 and is affiliated to both the NIHR Cambridge Clinical Research Facility and Wellcome - MRC Institute of Metabolic Science. Her interests relate to the applications of magnetic resonance, in particular to mitochondrial function as well as in studying insulin resistance.
Recent publications
Savage DB, Watson L, Carr K, Adams C, Brage S, Chatterjee KK, Hodson L, Boesch C, Kemp GJ, & Sleigh A. (2019). Accumulation of saturated intramyocellular lipid is associated with insulin resistance. The Journal of Lipid Research, 60, 1323-1332.
Charles-Edwards G, Amaral N, Sleigh A, Ayis S, Catibog N et al. (2019). Effect of iron isomaltoside on skeletal muscle energetics in patients with chronic heart failure and iron deficiency. Circulation, 139(21), 2386-2398.
Thankamony A, Kemp GJ, Koulman A, Bokii V, Savage DB, Boesch C, Hodson L, Dunger DB, & Sleigh A. (2018). Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis. Sci Rep, 8(1), 2750.
Stovell MG, Yan J-L, Sleigh A, Mada MO, Carpenter TA, Hutchinson PJA, & Carpenter KLH. (2017). Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications. Front Neurol, 8, 426.
Rocha N, Bulger DA, Frontini A, Titheradge H, Gribsholt SB et al. (2017). Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression. Elife, 6.
Internal collaborators at
Wellcome-MRC Institute of Metabolic Science, Cambridge
NIHR Cambridge Clinical Research Facility, Cambridge
Cambridge Intellectual and Developmental Disabilities Research Group, Cambridge
and Prof Patrick Chinnery, MRC Mitochondrial Biology Unit, Cambridge
and Prof Kevin Brindle, CRUK Cambridge Institute, Cambridge
External collaborators
Prof Graham Kemp, University of Liverpool, Liverpool, UK
Prof Leanne Hodson, University of Oxford, Oxford, UK
Prof Chris Boesch, University Bern, Switzerland