Group leader / Principal Research Associate
Wolfson Brain Imaging Centre
+44(0)1223 746460
ORCID: orcid.org/0000-0002-3859-8701
Alison's group designs novel magnetic resonance spectroscopy for use in metabolic research. Alison has worked at the WBIC since 2003 and is affiliated to both the NIHR Cambridge Clinical Research Facility and Wellcome - MRC Institute of Metabolic Science. Her groups interests relate to the applications of magnetic resonance, in particular to mitochondrial function as well as in studying insulin resistance.
Alison is very open to collaborative discussions about potential future studies that may use magnetic resonance spectroscopy.
Selected publications
Azhar M, Watson LPE, De Lucia Rolfe E, Ferraro M, Carr K, Worsley J, Boesch C, Hodson L, Chatterjee KK, Kemp GJ, Savage DB, & Sleigh A. (2024). Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores. NMR in Biomed, In press.
Meyerspeer M, Boesch C, Cameron D, Dezortova M, Forbes SC, Heerschap A, Jeneson JAL, Kan HE, Kent J, Layec G, Prompers JJ, Reyngout H, Sleigh A, Valkovic L, Kemp GJ, & Experts' Working Group on 31P MR Spectroscopy. (2021). 31P Magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations. NMR in Biomed, 34:e4246.
Savage DB, Watson L, Carr K, Adams C, Brage S, Chatterjee KK, Hodson L, Boesch C, Kemp GJ, & Sleigh A. (2019). Accumulation of saturated intramyocellular lipid is associated with insulin resistance. The Journal of Lipid Research, 60, 1323-1332.
Charles-Edwards G, Amaral N, Sleigh A, Ayis S, Catibog N et al. (2019). Effect of iron isomaltoside on skeletal muscle energetics in patients with chronic heart failure and iron deficiency. Circulation, 139(21), 2386-2398.
Thankamony A, Kemp GJ, Koulman A, Bokii V, Savage DB, Boesch C, Hodson L, Dunger DB, & Sleigh A. (2018). Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis. Sci Rep, 8(1), 2750.
Group members
Dr Mueed Azhar: Postdoctoral Research Associate
Kritika Grover: MPhil student
Internal collaborators at
Wellcome-MRC Institute of Metabolic Science, Cambridge
NIHR Cambridge Clinical Research Facility, Cambridge
Cambridge Intellectual and Developmental Disabilities Research Group, Cambridge
and Prof Patrick Chinnery, MRC Mitochondrial Biology Unit, Cambridge
and Prof Kevin Brindle, CRUK Cambridge Institute, Cambridge
External collaborators
Prof Graham Kemp, University of Liverpool, Liverpool, UK
Prof Leanne Hodson, University of Oxford, Oxford, UK
Prof Chris Boesch, University Bern, Switzerland